Job title: Associate Principal Scientist – Ophthalmology
Company: MSD
Job description: Job DescriptionOur company, a global healthcare leader, is seeking an Associate Principal Scientist to join our collaborative, dynamic, and inclusive Laboratory Animal Resources Team at the West Point, PA location.The successful candidate will have a key role in developing ophthalmic research models in pre-clinical species, specifically in support of our expanding ophthalmology portfolio. The candidate should be a collaborative individual with a high degree of sophistication in problem-solving and the ability to apply ophthalmic expertise to research needs. It is desirable for the candidate to have an understanding of laboratory animal medicine. In this dynamic role, the candidate will support preclinical projects across our company’s Research portfolio in early discovery and in the GLP environment. On-site and direct study-related lab work will be a crucial part of the role. The candidate should demonstrate strong leadership abilities that contribute to the growth and development of the ophthalmic research team within LAR and be capable of providing scientific guidance and mentoring to colleagues and junior staff members. It is crucial for this individual to exercise care to ensure both personnel safety and animal welfare.Responsibilities:Provide subject matter expertise to all aspects of the pipeline with a strong emphasis on ophthalmic research programs and the further development of existing and creating of new modalities and in vivo ophthalmic research models. May conduct or supervise the conduct of technical aspects of ophthalmic animal research projects in field of diabetic retinopathy/diabetic macular edema, age related macular degeneration, Neurological disease-induced ocular diseases (retinopathy), etc. Perform eye exams such as slit lamp, Indirect Ophthalmoscopy in all species of laboratory animals in GLP or non-GLP environment. Provides direction of ocular imaging operation such as Ocular Coherence Tomography, Fluorescein Angiography, Electroretinography, Tomography, etc. Provide direction for specialized ocular research needs, such as ocular surgery, ocular local injection (Intravitreal, subretinal injection, etc.) Provide professional teaching and training to colleagues and junior staff members with ophthalmic research related skill set. Familiar and experienced in artificial intelligence (AI) and machine learning (ML) for algorithms of ocular images such as retinal segmentation, etc. Conduct literature searches, selects appropriate animal model(s), contributes to study design, utilizes analyzing software for data analysis and interpretation and prepares reports. Team player who is a creative, independent thinker, thrives in a widely interdisciplinary environment, and enjoys working closely and communicating effectively with colleagues in extremely diverse fields. Experience working with various species in the laboratory animal field providing technical support to biomedical research projects, collaborating with researchers and research staff, training and teaching research and lab animal staff, and ensuring compliance with federal, state, local regulations and AAALACi standards. Ensure close collaboration with principal investigators in various functional areas, scientific staff, veterinarians, veterinary technicians, IACUC members, facility managers, and animal care technicians. Collaborate cross-functionally with ongoing in vivo discovery research and development projects, as well as initiate, develop, and implement special projects to facilitate advancements in laboratory animal care or use that align with ophthalmic research requirements. Advise investigators regarding animal model selection or development. Develop novel, and establish unique animal models as required. Maintain accurate, timely, digitalized, and well-organized records of research protocols, procedures, study data, inventories, and reports in both non-GLP and GLP platforms. Participates fully as a member of assigned project teams or task forces. Communicate study results and data interpretation to cross-functional project teams. Comply with US and our company-specific rules and regulations, e.g., Animal Welfare Act, The Guide for the care and use of laboratory animals, 3Rs (Replacement, Reduction, and Refinement) principles, FDA, and other regulatory bodies.Qualifications:Required:You should hold an advanced or professional degree (MD, PhD, DVM, or equivalent)You have at least 2 years of experience in the field of ophthalmology in pre-clinical species, either in an industry or academic setting.You should be comfortable doing eye exams such as slit lamp, Indirect Ophthalmoscopy to all species of laboratory animal in GLP or non-GLP environment, Ocular Coherence Tomography, Fluorescein Angiography, Electroretinography, Tomography, etc.Demonstrable passion for animal care and welfare.Willingness to learn technical and scientific skills and a comprehensive understanding of the R&D process.Ability to independently recognize challenges (scientific, or study-related) and provide relevant input for solution/problem solving.Initiative-taking, innovative, and solution-oriented mindset.Excellent organizational, interpersonal, and communication skills.Commitment to maintaining highest safety and regulatory standards.Preferred:Board Certification in OphthalmologyExperience working in a GLP environment.Proven history in performing basic and extensive routine eye exams in various laboratory animal species in the preclinical environment.Our company’s values collaboration, coordination, and communication. We aim to foster an atmosphere of mutual respect and provide a vibrant learning environment where new skills can be honed, and innovative solutions can be explored. If you are interested in contributing to our research within a dynamic team that prioritizes respect and collaboration, we would love to hear from you.NOTICE FOR INTERNAL APPLICANTSIn accordance with all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.Current Employees applyCurrent Contingent Workers applyUS and Puerto Rico Residents Only:Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please if you need an accommodation during the application or hiring process.We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.U.S. Hybrid Work ModelEffective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.Employee Status: RegularRelocation: Domestic/InternationalVISA Sponsorship: YesTravel Requirements: 10%Flexible Work Arrangements: Not ApplicableShift: 1st – DayValid Driving License: NoHazardous Material(s): n/aJob Posting End Date: 09/5/2024*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Expected salary:
Location: West Point, PA
Job date: Sat, 24 Aug 2024 02:46:25 GMT
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